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September 2009
Volume 2, Number 3
Cover Illustration:

The cover represents an artistic depiction of results described in the paper by Grunewald et.al. wherein the integration of signals from the extracellular matrix through the cell surface into the nucleus is explained.

TABLE OF CONTENTS

Brief Article

Expression of zonulin, c-kit and glial fibrillary acidic protein in human gliomas

Marco Skardelly, Franz Paul Armbruster, Juergen Meixensberger and Heidegard Hilbig

Abstract   Full Article

Acute vascular disruption by 5,6-dimethylxanthenone-4-acetic acid in an orthotopic model of human head and neck cancer

Mukund Seshadri and Karoly Toth

Abstract   Full Article

Original Report

Bcl6 is expressed in neuroblastoma: Tumor cell type specific expression predicts outcome

Aghiad Chamdin, Jason A. Jarzembowski, Chitra Subramanian, Rork Kuick, Julia Shin-Jung Lee, Roland Kwok, Valerie P Castle and Anthony W Opipari Jr.

Abstract   Full Article

Cancer abolishes the tissue-type specific differences in the phenotype of energetic metabolism

Acebo Paloma, Daniel Giner, Piedad Calvo, Blanco-Rivero Amaya, Alvaro D Ortega, Pedro L Fernández, Giovanna Roncador, Fernández-Malavé Edgar, Margarita Chamorro and José M Cuezva

Abstract   Full Article

Evidence of heavy methylation in the galectin-3 promoter in early stages of prostate adenocarcinoma: Development and validation of a methylated marker for early diagnosis of prostate cancer

Hafiz Ahmed, Francesco Cappello, Vito Rodolico and Gerardo R. Vasta

Abstract   Full Article

Altered microRNA expression patterns in hepatoblastoma patients.

Armando Magrelli, Gianluca Azzalin, Marco Salvatore, Mara Viganotti, Fabrizio Tosto, Teresa Colombo, Rita Devito, Alessandra Di Masi, Antonio Antoccia, Stefano Lorenzetti, Francesca Maranghi, Alberto Mantovani, Caterina Tanzarella, Giuseppe Macino and Domenica Taruscio

Abstract   Full Article

Combination of enzastaurin and pemetrexed inhibits cell growth and induces apoptosis of chemoresistant ovarian cancer cells regulating ERK1/2 phosphorylation

Karen Braeutigam, Dirk Bauerschlag, Marion T. Wiegel, Julia Biernath-Wuepping, Thomas Bauknecht, Norbert Arnold, Nicolai Maass and Ivo Meinhold-Heerlien

Abstract   Full Article

Preclinical efficacy of cystatin C to target the oncogenic activity of TGF-â in breast cancer

maozhen Tian and William P. Schiemann

Abstract   Full Article

A feasibility study of parametric response map analysis of DW-MRI scans of head and neck cancer patients for providing early detection of therapeutic efficacy

Craig J Galban, Suresh K Mukherji, Thomas L Chenevert, Charles R Meyer, Daniel A Hamstra, Peyton H Pland, Timothy D Johnson, Bradford A Moffat, Alnawaz Rehemtulla, Avraham Eisbruch and Brian D. Ross

Abstract   Full Article

Recent progress in cancer therapeutics

Kurt Zaenker, Enrico Mihich and Princess Chulabhorn Mahidol

Abstract   Full Article

Review

Cell-adhesion and transcriptional activity – defining the role of the novel proto-oncogene LPP

Thomas GP Grunewald, Saskia M Pasedag and Elke Butt

Abstract   Full Article

 
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